Literature Compendium

PCT Literature Compendium

Procalcitonin (PCT) is now recognized as a marker for assessing sepsis risk and progression, and as a tool for guiding antibiotic therapy.

The ten articles comprising this compendium address these usages in different clinical care settings for pathologies of varying severity, and also provide evidence of the financial benefit of using PCT.

PCT Literature Compendium mockup

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From the compendium Are calcitonin precursors reliable markers of sepsis in a medical ICU?


  • Investigate the ability of calcitonin precursors (i.e., procalcitonin [PCT]) to aid in the diagnosis of bacterial sepsis.
  • Compare the diagnostic accuracy of PCT to that of other markers used in critical care practice.

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PCT Literature compendium graph

Percent difference of mean biomarker levels between patients with confirmed bacterial infection and those with negative cultures.